From Prompt Rules to Golden Data Model: Production-Scale Generation of Personalized, Compliant Pharmaceutical Claims

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Large language models (LLMs) are increasingly used to generate domain-specific commercial & medical content (e.g., claims, statements, and promotional phrases) in regulated industries such as pharmaceuticals. However, ensuring its regulatory compliance, factual accuracy, and audience-specific personalization remains a major challenge. We report a production case study asking whether moving compliance and personalization signal from prompt-level rules into retrieval time structured context improves pharmaceutical claims generation, using Composer, a deployed internal tool built on a Golden Data Model (GDM) of 1,867 pharmaceutical claims spanning four products. The GDM integrates claim metadata, references, audience labels, material type, usage history, Match Text Variant (MTV) links, and a six dimension quality score (6C). Across six product-audience segments, the context pipeline improves intended indication (+29%), intended content type (+62%) and intended target audience (+67%), 6C quality score (+86%), and claim reuse (+34%). Production log analysis over the deployment period shows a 29.5% reduction in weekly API cost. We report this as descriptive deployment evidence. This work is a systems and data architecture contribution: it shows that in a regulated, high-stakes domain, restructuring claim data for retrieval-time filtering is a more scalable lever than expanding prompt-level rules, and documents the engineering path data cleaning, graph linking, and quality scoring.

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